Our work contributes to the understanding of the molecular-level phenomenon of tolerance that occurs with regular cannabis use. Benjámin Barti, a highly talented PhD student of the group, was the lead author of the publication. The credit also goes to Beni for the artistic depiction of a pyramidal neuron featured on the cover page. The rainbow-coloured dots represent cannabinoid receptors on the surface of an incoming axon giving an inhibitory synapse on the pyramidal neuron.
Congratulations to Beni on defending summa cum laude his PhD thesis: “Regulation of the tonic endocannabinoid signaling pathway in hippocampal inhibitory cells”.
The study introduces PharmacoSTORM a novel method based on fluorescent small molecule pharmacoprobes (receptor ligands and enzyme inhibitors) and STORM super-resolution imaging.
