Investigation of the basic mechanisms of absence epilepsy

We would like to identify those elements of the thalamocortical circuitry which are involved in the initiation and maintenance of epileptic events

Absence epilepsy is a chronic disease characterized by non-convulsive seizures, behavioral arrest, loss of consciousness and lack of responsiveness to external stimuli. It is known that seizures originate in the cerebral cortex, from where they spread to other cortical areas with the active contribution of the thalamic region, mainly mediated by thalamocortical connections.

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