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The effect of cannabis on synapses

From time to time, there are topics that many people think a little knowledge gleaned from the internet is enough to decide for themselves what the truth is. Just as during the pandemic, many believed it was best to decide for themselves which vaccines to trust and whether vaccination was necessary, there is a strong difference of opinion on the use of marijuana, which many consider to be an 'innocent' pleasure item. But what is the truth? What is known today about the active ingredients of marijuana and the causes of its physiological effects? To play on the title of a famous old film, what is the effect of cannabis on the synapses? 

How does the brain learn from negative experiences?

Balázs Hangya and his team studied deep brain inhibitory cells and observed that when these cells were blocked, the mice did not learn from the negative stimuli they received. The significance of their discovery is reflected in the fact that their work has been accepted for publication in the journal Nature Communications.

István Katona's article on the front page of Science Advances

The results published in the highly prestigious journal Science Advances, with Benjámin Barti as the first author, contribute to the understanding of the phenomenon of tolerance accompanying the regular consumption of cannabis at the molecular level.

Varietas delectat

Using a combination of state-of-the-art physiological and anatomical methods, Zoltán Nusser's group has succeeded in discovering how an axon of the same nerve cell can form synapses of different strengths with two different nerve cells. Short answer: synaptic vesicles are in different maturation states in weak and strong synapses. Their work was published in Neuron.

Exceptional teamwork, exceptional results. In the margin of a PLoS Biology article

In a paper published in the prestigious journal Plos Biology, Gábor Nyiri, and his team present anatomically accurate active and passive model cells of two different interneurons that can be used to incorporate further experimental data and thus be used in a variety of ways to interpret the results of different physiological experiments and to create neural network models simulating hippocampal function. The paper has not one, but five first authors, which is unusual, to say the least, but which is perfectly understandable once you get to know the work.

Ádám Denes wins the Academy Prize

At its 197th General Assembly, the Presidium of the Hungarian Academy of Sciences awarded the Academy Prize to Ádám Dénes, head of the Neuroimmunology research group, for his versatile and highly successful scientific activities. Hearty congratulations on this well-deserved honor!

A liitle news about a Grand Prize

At the XXIV Carpathian Basin Conference of Scientific Student Circles, Emil Koplányi, mentored by Dr. Imre Kalló, won the Grand Prize in the Theoretical and Experimental Medicine section of the Performed Research Block. Congratulations!

Our talented researchers

Academician László Acsády, who, together with his team at our institute, initiated and brought to world-class recognition the research of the thalamus, one of the main communication partners of the cerebral cortex, received the Talentum Prize, founded by the National Academy of Scientist Education, on 15 April 2024.

A RICHTER-KOKI press conference. Background and vision

Richter Gedeon Plc. and KOKI have been working together successfully for decades, but on 5 April 2024 they held their first joint, and international, press conference. 

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