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When the Memory Brings Fear Once Again

No researcher need fear that one day there will be nothing left to discover.

Our understanding of the brain’s anatomy is not yet complete, even though its first comprehensive scientific map—the Brodmann map, which remains well-known today—was published as early as 1909; a hundred years later, in 2011, the Allen Institute for Brain Science published the first genetic map of the human brain, and since 2013, anyone has been able to explore a three-dimensional digital model of the human brain with a resolution of 20 micrometers,  and with the help of modern imaging techniques and cell-level analyses, there is still a chance today for anyone who asks the right questions, possesses excellent knowledge of neuroanatomy and methodology, and is not afraid of long-term work to discover previously unidentified clusters of neurons—known in neuroanatomy as “nuclei.”

 Gábor Nyiri and his team have already discovered a brainstem region that plays a key role in processing emotions and regulating motivational processes; in their paper just published in Nature Communications, they describe a neural circuit that links memory recall to the fear response.

"Transcriptome profiling"

The work of our institute’s Reproductive Neurobiology Research Group was published in the August 2026 issue of Nature Communications. Group leader Erik Hrabovszky, who directed and organized the work, is the last author of the article, and Szabolcs Takács, a member of his group and the first author of the publication, answers our questions.

How the Brain Links Fear to Negative Memories

When we recall an unpleasant memory, we do not simply replay it as detached observers watching a scene from a film: we often re-experience the emotion, including the fear, associated with the original event. Researchers at the HUN-REN Institute of Experimental Medicine are helping to explain how the brain links the retrieval of a memory to the accompanying feeling of fear. Their findings shed light on how persistent activity in this system may contribute to anxiety, post-traumatic stress disorder and depression.

Vaccination even during pregnancy is recommended

A new study in mice has found that COVID-19 or influenza vaccination during pregnancy does not cause the neurological changes that a real infection can trigger in the offspring. Researchers at the HUN-REN Institute of Experimental Medicine found that a treatment mimicking a viral infection produced a lasting, autism-like behavioural pattern in mouse pups, whereas the vaccines caused only mild, transient differences. The results therefore point clearly in favour of getting vaccinated.

A Key Protein Tunes the Strength of Communication Between Nerve Cells

Every time one nerve cell communicates with another, small structures at the synapse called vesicles release chemical messengers into the synaptic cleft between the cells. Before a vesicle can release its contents, however, it must first be prepared, or “primed” for release. The new study by Aldahabi and colleagues examines how this priming step affects the strength and diversity of connections between nerve cells.

Balázs Göcz won the Bolyai Research Fellowship

Several researchers from our institute also applied for the Bolyai Fellowship, the most prestigious scholarship for young researchers in Hungary, which was awarded this year to Balázs Göcz. Congratulations!

Everything you want to know and see about microglia...

Although neuroimmunology was already an established branch of neuroscience research by the 1980s, its recognition was nowhere near what it is today.

Closing conference of National Bran Research Program 3.0

As with previous events, the fourth and final conference of the National Brain Research Program (NAP) 3.0 was held at the Puchner Estate in Bikal.  

 

Kati Lengyel's award

The Association of Women in Science (NaTE), which won the first Nature Innovating Science Award established by Nature and the Estee Lauder Company in 2018, began in 2008 with just 10 female researchers, with the goal of supporting women and girls in pursuing careers in science and technology. In 2013, the first Women in Science Excellence Award, established to recognize female researchers working in the fields of engineering, physics, astronomy, and space research, was presented; in recent years, the award has also been given to support research activities. This latter award was won by Katalin Lengyel, a research assistant in Balázs Hangya’s group.

 

 

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