Selenodeiodinase Processing by the Proteasome System
The goal of the project is to understand the cellular and molecular mechanism regulating tissue-specific thyroid hormone signalling in the brain and find differences in how cells react to thyroxine (LT4), ubiquitinate/deubiquitinate type 2 deiodinase and produce T3, with impact on TH signaling and LT4 therapy
NKFI 125247-(National Research, Development and Innovation Office of Hungary) 2017-2022
Tissue specific assessment of medical therapy evoked alterations of thyroid hormone economy in rodents and humans
The goal of this project is to understand tissue thyroid hormone action in amiodaron treated THAI mouse and find human markers of tissue-specific TH action.
NRDI Hungarian Brain Research Program 2.0 2017-2022
Cell-type specific assessment of thyroid hormone economy in neurosecretory neurons of live mice
The goal of this project is to develop in vivo approaches to asses thyroid hormone levels in neurons of live mice